Posts Tagged ‘IFN Gamma ELISA kit’

What is IFN Gamma ELISA?

Monday, March 15th, 2021

Interferon‐gamma or IFN‐γ is a cytokine that plays a significant role in causing and regulating a variety of immune reactions.  Cellular responses to IFN‐γ are mediated with its heterodimeric cell‐surface receptor, which triggers downstream signal transduction cascades, finally resulting in the regulation of gene expression.

To be able to study the function of IFN‐γ in several immune pathways and responses, researchers have developed mice with varied patterns of IFN‐γR receptor expression. You can know more about IFN gamma ELISA at

These studies, as well as investigations of naturally occurring mutations of those IFN‐γR in a person, are instrumental in elucidating the varied purposes of IFN‐γ. The Human Interferon-gamma or Hu IFNγ ELISA measures Hu IFN γ in human serum, plasma, or cell culture medium.  The assay will comprehend both natural and recombinant Hu IFNγ.

The Individual IFNγ solid-phase sandwich ELISA was created to quantify the amount of this goal-bound involving a coordinated antibody pair. A target-specific antibody was pre-coated from the wells of their provided microplate.  Samples, criteria, or controllers are subsequently added within these molds and bind to the immobilized antibody.

The sandwich is formed by the inclusion of the next antibody, a substrate solution has added that response with the enzyme-antibody-target complicated to make the measurable signal. IFN gamma is a macrophage activation factor, and IFN gamma gene mutations are associated with aplastic anemia.